The Vitality bonus on amulets is a bit wasted, as you will mostly only take direct health damage if you have lost your armor. Small runes gain +1, Medium and Large +2, and Giant +3.Įarth weapons are in an interesting position, with slight favoritism towards using an Earth damage staff or two-handed Strength weapon. Frames of Power instead give boosts to direct damage attributes, based on rune size. Mystical Frames will grant mostly a +1 increase to combat abilities the exception being Masterwork runes that instead give +3 to secondary attributes like Memory or Wits. This means aim to only place Large or Giant size runes into a frame.
However, once a rune is placed in a frame it can never be removed.
Bigger runes will have increased bonuses, making it worthwhile to increase their size.